Regulatory perspective - Hazard and
risk identification of plant protection products, industrial chemicals, new
chemical entities, pharmaceuticals, and personal care products to aquatic and
terrestrial ecosystems in OECD recommended model systems (Algae, Daphnia,
Zebrafish, Earthworm, Honeybee, Japanese Quail) based on national and
international regulatory guidelines as per the OECD principles of GLP. The data
generated will be helpful for
the regulators / implementing agencies to classify the category of products in
terms of consumer safety and environmental health protection.
v R&D perspective
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Deciphering the underlying cellular
and molecular mechanisms of neurodevelopmental and complex behavioral toxicity
by emerging environmental contaminants such as organic UV filters (OUVF),
microplastics, flame retardants etc. in developing zebrafish (Danio rerio) model.
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Interaction and toxicity of
microplastics and PAHs (US EPA prioritized) on vertebrate early development using Danio rerio.
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Exploring the earthworm, Eisenia
fetida as suitable terrestrial sentinel model to assess the detrimental
impacts of emerging contaminants (OUVF, microplastics, PAHs, biodegradable
plastic additives, and novel flame retardants etc.)
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Impact of emerging contaminants
on crustacean growth, development and reproduction in Daphnia magna
model using multi-omics approach.