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Scientific Staff

Dr. Sandeep Kumar Sharma
Senior Scientist
Food, Drug & Chemical Toxicology
CSIR-Indian Institute of Toxicology Research
Vishvigyan Bhawan, 31, Mahatma Gandhi Marg
Lucknow - 226 001. Uttar Pradesh, India.
Email: sharma.sandeep[at]iitr.res.in | Alternate Email: NA
Tel: +91-522-2217497 | Extension: 767
Fax: 522-2628227

Areas of Specialization
Biochemistry & Biophysics
Current R&D/S&T Activities

Food safety & quality assessment

Consumption of food containing adulterants and contaminants cause several diseases. To empower the consumer and regulatory agencies, our aim is to develop methods and sensors for detection of adulterants and contaminants in food commodities. 

 

Functionality and mechanism of molecular chaperones & metal induced toxicity

Protein misfolding and aggregation under stressful environmental conditions may lead to neurological disorders like Parkinson’s disease (PD), Alzheimer’s disease (AD), Amyloid lateral sclerosis and Huntington disease (HD). Molecular chaperones play a major role in preventing protein misfolding by mediating proper native folding, unfolding and refolding of the polypeptides along-with vast number of other cellular functions. We use various biochemical and biophysical approaches to decipher the mechanism of molecular chaperones and metal induced toxicity.


Partial List of Research Publications